Cirrhosis

Study pinpoints genetic and environmental factors of primary biliary cirrhosis

Published in Hepatitis Weekly, November 21st, 2005

A case-control study of more than 2000 people has identified a number of factors that may induce primary biliary cirrhosis (PBC) in genetically susceptible individuals. These include a history of urinary tract infections, hormone replacement therapy, tobacco use, and nail polish use.

The study is published in the November 2005 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD).

PBC is a rare autoimmune disease that leads to liver failure. The cause of the disease is unknown. It is more prominent in women, and researchers have found instances of familial clustering, as well as...

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Source: Hepatitis Weekly (2005-11-21)

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