Hepatitis C Virus
p53, p21ras and mdm2 alterations are late events in hepatocarcinogenesis
Published in Hepatitis Weekly, December 5th, 2005
"The non-structural protein 3 (NS3P) of hepatitis C virus (HCV) genome was linked to the neoplastic transformation of normal hepatocytes in chronically infected patients. However, the exact mechanisms involved in this process are unidentified yet, especially in the Egyptian population where the commonest type is genotype 4."
"We investigated 32 HCV reverse transcriptase-polymerase chain reaction (RT-PCR) positive hepatocellular carcinoma (HCC) cases and 18 morphologically normal hepatic tissues distant to tumors (MNT) for...
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Source: Hepatitis Weekly (2005-12-05)
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