Hepatitis B Virus
Stable inhibition of hepatitis B virus proteins is achieved by viral vector RNA
Published in Hepatitis Weekly, December 5th, 2005
"There has been much research into the use of RNA interference (RNAi) for the treatment of human diseases. Many viruses, including hepatitis B virus (HBV), are susceptible to inhibition by this mechanism."
"However, for RNAi to be effective therapeutically, a suitable delivery system is required. Here we identify an RNAi sequence active against the HBV surface antigen (HBsAg), and demonstrate its expression from a polymerase III expression cassette,"...
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Source: Hepatitis Weekly (2005-12-05)
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