Disease Associations

Detection of alpha-fetoprotein mRIVA in hepatitis patients may aid in cancer therapy

Published in Hepatitis Weekly, December 26th, 2005

Recent research from the People's Republic of China has reported on the detection of alpha-fetoprotein (AFP) mRNA in peripheral blood of the patients with hepatocellular carcinoma (HCC), liver cirrhosis (LC) and hepatitis.

"The low frequency of disseminated carcinoma cells in the blood now makes immunomagnetic bead sorting and reverse transcriptase-polymerase chain reaction (RT-PCR) technique more popular," wrote F. Yao and colleagues, Ningbo University.

"Three milliliters of peripheral blood were collected from 91 patients and 18 normal donors. The circulating carcinoma cells were enriched with CD45 and Ber-EP4 immunomagnetic beads."

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Source: Hepatitis Weekly (2005-12-26)

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