Proteomics
Engineered apolipoprotein A-I mutant is useful for structural determination
Published in Hepatitis Weekly, January 9th, 2006
According to researchers in the United States, "Apolipoprotein A-I (apoAI), the major protein component of HDL, is one of the best predictors of coronary artery disease (CAD), with high apoAI and HDL levels being correlated with low occurrences of CAD. The primary function of apoAI is to recruit phospholipid and cholesterol for assembly of HDL particles."
X.F. Ren and colleagues at Wayne State University explained, "Like other exchangeable apolipoproteins, lipid-free apoAI forms a mixture of different oligomers even at 1.0 mg/mL. This...
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Source: Hepatitis Weekly (2006-01-09)
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