Liver Disease

Serum nuclear matrix protein levels are diagnostic of organ damage in liver disease

Published in Hepatitis Weekly, January 30th, 2006

Recent research from Japan has clarified the clinical implications of measurement of serum nuclear matrix protein (NMP) levels in patients with liver disease.

"Serum aminotransferase, a sensitive marker of hepatocellular damage, often poorly correlates with the severity of damage. Serum NMP, a structural protein released from dead cell nuclei, is investigated as a candidate marker of organ damage in liver disease."

Y. Shimizu and colleagues, Nagoya University, wrote, "Serum NMP and aminotransferase levels of 134 patients with various liver diseases and 26 healthy individuals were examined."

"Patients with chronic viral hepatitis...

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Source: Hepatitis Weekly (2006-01-30)

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