Published in Hepatitis Weekly, February 6th, 2006
S.G. Park and colleagues, Seoul National University, wrote, "We report the construction of a large nonimmunized human phage antibody library in single-chain variable region fragment (scFv) format, which allowed the selection of antibodies that neutralize HBV in vitro."
"We generated 1.1 x 1010 independent scFv clones using the cDNA of functional variable (V) gene segments of heavy and light chains purified from the peripheral blood mononuclear cells of 50 nonimmunized human donors."
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