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Hepatitis C Virus

Researchers' data advance hepatitis C virus research

Published in Hepatitis Weekly, February 13th, 2006

Data on hepatitis C virus are outlined in reports from Germany, Taiwan and the United States.

Study 1: According to research from Germany, hairpin ribozymes (Rz) in combination with siRNAs against highly conserved hepatitis C virus sequence inhibit RNA replication and protein translation from hepatitis C virus (HCV) subgenomic replicons.

"Chronic HCV infection is a clinically important liver disease with limited therapeutic options in a significant proportion of patients. Therefore, novel efficient therapeutic agents are needed," wrote D. Jarczak and colleagues, Hannover Medical School

"Because the 5'- and 3'-untranslated regions...

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