Published in Hepatitis Weekly, February 13th, 2006
G. Szabo and colleagues, University Massachusetts, wrote, "Toll-like receptors (TLR) recognize pathogen-derived molecules and induce downstream activation of inflammatory pathways. Fatty liver has been shown to result in increased sensitivity to lipopolysaccharide a (LPS), a TLR4 ligand."
"In this study, we investigated the roles of TLR2 and TLR4 in liver damage and on cytokine induction in a Met-Cho deficient (MCD) diet-induced model of nonalcoholic steatohepatitis."
"We found that...
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