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Hepatitis C Virus

Serum and liver viral markers evolve during long-term HCV treatment and response

Published in Hepatitis Weekly, February 13th, 2006

A study from Spain has chronicled the long-term evolution of serum and liver viral markers in patients treated for chronic hepatitis C (CHC) and sustained response.

"Few studies have analyzed the evolution of HCV markers in CHC-treated patients. We have evaluated the presence or absence of serum and liver HCV-RNA, the core antigen (HCV-cAg) and the loss of specific antibodies (anti-HCV), in long-term sustained responders (SR)," wrote M. Moreno and colleagues, Hospital Central de Asturias.

"One hundred and seventy-six patients (132 SR and 44 nonresponders [NR]) were included in the study. HCV-RNA was determined in serum and liver by a commercial...

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