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Hepatitis A Virus

HAV vaccine responses occur in HIV-infected children during HAART

Published in Hepatitis Weekly, February 20th, 2006

A study from the United States has reported on antibody responses to hepatitis A virus (HAV) vaccine in human immunodeficiency virus (HIV)-infected children with evidence of immunologic reconstitution while receiving highly active antiretroviral therapy (HAART).

"HIV-infected patients have weak responses to vaccines and may require revised immunization regimens. We investigated the safety and immunogenicity of 2 doses of HAV vaccine followed by a booster dose in HIV-infected children receiving stable HAART," wrote A. Weinberg and colleagues, University of Colorado Health Sciences Center.

"A total of 235 children with CD4+ T cell percentages...

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