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Hepatitis C Virus

Anti-hepatitis C virus antibody quantified in patients with chronic hepatitis C

Published in Hepatitis Weekly, March 6th, 2006

Researchers in the United States conducted a study that reported on the quantification of anti-hepatitis C virus antibody in patients with chronic hepatitis C.

"To investigate the quantitative characteristics of humoral immunity in patients with hepatitis C, we established an enzyme-linked immunosorbent spot (ELISpot) assay for detection of anti-hepatitis C virus (HCV)-secreting B cells," wrote T. Umemura and colleagues, U.S. National Institutes of Health.

"Receiver operating characteristic curve analysis demonstrated 100% specificity and 58% to 92% sensitivity for detecting B-cell responses to NS5b, NS3, E2, and core antigens."

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