Hepatitis C Virus
Reports advance knowledge in hepatitis C virus research
Published in Hepatitis Weekly, March 27th, 2006
Study 1: Research from the United States has reported that the polypyrimidine tract-binding protein (PTB) is required for efficient replication of hepatitis C virus (HCV) RNA.
"Our earlier work found that the PTB specifically interacts with the poly(U/C) tract of the HCV 3' untranslated region (3'UTR) [Luo, G., 1999. Cellular proteins bind to the poly(U) tract of the 3' untranslated region of hepatitis C virus RNA genome. Virology 256, 105-118]."
"We report here that the phosphorylated form of PTB is associated with the membrane-bound HCV...
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Source: Hepatitis Weekly (2006-03-27)
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