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Proteomics

Clinically relevant protein-peptide interactions can be monitored in real time

Published in Hepatitis Weekly, March 27th, 2006

According to a study from France, clinically related protein-peptide interactions can be monitored in real time on novel peptide chips by surface plasmon resonance imaging.

"Developing rapid, high-throughput assays for detecting and characterizing protein-protein interactions is a great challenge in the postgenomic era. We have developed a new method that allows parallel analysis of multiple analytes in biological fluids and is suitable for biological and medical studies.

"This technology for studying peptide-antibody interactions is based on polypyrrole-peptide chips and surface plasmon resonance imaging (SPRi)," wrote B. Cherif and colleagues,...

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