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Transplantation Biology

Post-liver transplantation virus reinfection can be delayed by early therapy

Published in Hepatitis Weekly, April 3rd, 2006

According to a study from the United States, early therapy can delay hepatitis C virus (HCV) reinfection after liver transplantation.

"Improved understanding of HCV dynamics during and after liver transplantation can be useful in optimizing antiviral therapy in transplant recipients," wrote K.A. Powers and colleagues, Los Alamos National Laboratory. "We analyzed serum HCV ribonucleic acid (RNA) levels during and after cadaveric liver transplantation in 6 HCV patients. After removal of the liver and before the new liver started producing virions, HCV RNA levels dropped with an average half-life (t(1/2)) of 0.8 hours."

The scientists observed, "Viral...

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