DNA Vaccine
DNA vaccination elicits anti-HBV immune responses in rhesus macaques
Published in Hepatitis Weekly, April 24th, 2006
"Electroporation has been shown to be an effective method to improve the efficiency of gene expression and the immunogenicity of DNA vaccines," wrote Y.G. Zhao and colleagues, Shanghai Jiao Tong University. "In order to optimize the procedure and test for its efficacy in more clinically relevant large animal models, we examined the detailed immune responses in rhesus macaques after vaccination intramuscularly with electroporation using the plasmid encoding for HBV preS(2)-S antigen and an adjuvant plasmid encoding for hIL-2 and...
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Source: Hepatitis Weekly (2006-04-24)
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