HIV/AIDS

Reports from the United States and Japan add new data to HIV/AIDS research

Published in Hepatitis Weekly, May 1st, 2006

Data on HIV/AIDS are outlined in reports from the United States and Japan.

Study 1: A study from the United States has chronicled virologic and enzymatic studies that revealed the mechanism of K65R- and Q151M-associated human immunodeficiency virus (HIV)-1 drug resistance towards emtricitabine (FTC) and lamivudine (3TC).

"FTC and 3TC are deoxycytidine analogues with potent and selective inhibition of HIV and hepatitis B virus (HBV) replication. The K65R mutation in the HIV reverse transcriptase (RT) confers reduced susceptibility to 3TC, ddC, ddI, abacavir, and tenofovir in vitro," wrote J.Y. Feng and colleagues, Gilead Science Inc.

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Source: Hepatitis Weekly (2006-05-01)

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