Published in Hepatitis Weekly, June 12th, 2006
Study 1: Recent research from Cuba has reported on the expression and processing of hepatitis C virus (HCV) structural proteins in Pichia pastoris yeast.
"Development of heterologous systems to produce useful HCV vaccine candidates is an important part of HCV research. In this study different HCV structural region variants were designed to express the first 120 aa, 176 aa, 339 aa, and 650 aa of HCV polyprotein, and aa 384 to 521, or aa 384-605 or aa 384-746 of HCV E2 protein fused to the leader sequence of sucrose invertase 2 allowing the secretion of recombinant...
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Source: Hepatitis Weekly (2006-06-12)
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