Hepatitis B Virus

Hepatitis B core antigen variants display similar immunological effects

Published in Hepatitis Weekly, June 19th, 2006

According to recently published research from Cuba, hepatitis B virus (HBV) core antigen (HbcAg) variants display similar immunogenicity and immunoenhancing effects.

"HBcAg is a potent immunogen in animal models and humans and has been used as a carrier for several antigens; however, the mucosal immunogenicity of HBcAg has been poorly studied. In this study, we explored the immunogenicity and the immunoenhancing effect elicited by two different variants of the recombinant complete nucleocapside of HBV in mice by intranasal route," wrote Y. Lobaina and colleagues, Center of Genetics Engineering & Biotechnology.

They explained, "For this purpose, we...

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Source: Hepatitis Weekly (2006-06-19)

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