Published in Hepatitis Weekly, July 3rd, 2006
"We previously established HCV replicon-harboring cell lines possessing two IFN-resistant phenotypes: a partially resistant phenotype (alpha R series) and a severely resistant phenotype (OR series)," wrote K. Naka and colleagues, Okayama University.
They continued, "We recently found that the severe IFN resistance of the OR-series cells is caused by the functional disruption of type I IFN receptors. Here, we aimed to clarify the mechanism(s) underlying the...
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