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Chronic Liver Disease

Chronic liver disease progression involves the hepatic growth hormone receptor

Published in Hepatitis Weekly, July 10th, 2006

Researchers in Italy reported that hepatitis C virus (HCV)-related chronic liver disease progression involves a subcellular shift of the hepatic growth hormone receptor (GHR).

U.V. Gentilucci and colleagues, University of Rome Campus of Biomedicine, wrote that the study was done "to evaluate the cytoplasmic and nuclear expression of hepatic growth hormone receptor (GHR) in different stages (S-0, S-1, S-3 and S-4, according to Knodell's classification) of chronic liver disease (CLD) and in hepatocellular carcinoma (HCC)."

"Liver specimens from 31 patients with hepatitis C virus-related CLD, five patients with HCC and nine controls were examined for...

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