Hepatitis C Virus
Hepatitis C virus NS2 and NS3 proteins form a complex
Published in Hepatitis Weekly, July 10th, 2006
"HCV NS2 and NS3 proteins as well as the NS3 protease cofactor NS4A are essential for the replication of the virus. The presence of in vivo heterodimeric complex between HCV NS2 and NS3 has been suggested by biochemical studies.
"Detailed characterization of the interactions between these viral proteins is of great importance for better understanding their role in viral replication cycle and represents attractive target for antiviral agents. In this study, we demonstrated in vivo...
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Source: Hepatitis Weekly (2006-07-10)
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