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Hepatitis C Virus

Hepatitis C virus recombinant multiepitope protein functions diagnostically

Published in Hepatitis Weekly, July 10th, 2006

According to recent research from India published in the journal Protein Expression and Purification, a novel recombinant multiepitope protein is a hepatitis C diagnostic intermediate of high sensitivity and specificity.

"A novel recombinant multiepitope protein has been designed that consists of six linear, immunodominant, and phylogenetically conserved epitopes from hepatitis C virus," wrote C.A. Dipti and colleagues, International Center of Genetic Engineering & Biotechnology.

"Five of these antigens (core, NS3, NS4I, NS4II, and NS5) are being used in many of the third-generation kits while sixth epitope (core3g) is an additional sequence...

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