Published in Hepatitis Weekly, July 24th, 2006
"We evaluated the potential of DCs engineered to express antigen of hepatitis B virus (HBV) in priming Th/Tc and HBV-specific CTL responses in mice," wrote Y. Huang and colleagues, Zhejiang University.
"Recombinant adenovirus expressing HBsAg (Ad-S) was constructed, and bone marrow-derived DCs were transduced with Ad-S or pulsed with HBsAg protein. Mice were-S-transduced DCs or HBsAg-pulsed DCs or plasmid DNA encoding HBsAg injected with either Ad twice at...
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