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Hepatitis C Virus

Hepatitis C virus RNA is detectable in the liver of RNA-negative patients

Published in Hepatitis Weekly, August 14th, 2006

According to recent research published in the Journal of Infectious Diseases, hepatitis C virus (HCV) RNA is detectable in the liver of healthy, anti-HCV antibody-positive, serum HCV RNA-negative patients with normal Ala aminotransferase (ALT) levels.

"It is unknown whether HCV is present in the liver of anti-HCV antibody positive patients with persistently normal ALT levels and undetectable serum HCV RNA levels," wrote V. Carreno and colleagues, Foundation Estudio Hepatitis Virales.

They explained, "We determined the presence of genomic and antigenomic HCV RNA strands in liver biopsy specimens and peripheral blood mononuclear cell (PBMC)...

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