Hepatitis C Virus

Sensitivity to hepatitis C virus therapy may change after liver transplantation

Published in Hepatitis Weekly, September 11th, 2006

According to recent research from Spain, sensitivity to hepatitis C virus (HCV) therapy changes after liver transplantation (LT).

"In HCV-infected patients, it is generally assumed that the pattern of response to antiviral therapy remains unaltered after LT. However, changes in the circulating HCV quasispecies and in the gene expression profiles of the graft might influence response to treatment after LT," wrote A. Feliu and colleagues, Institut d'Investigacions Biomediques August Pi i Sunyer.

"We evaluated 22 HCV-infected patients who received antiviral treatment while awaiting LT and in whom HCV infection recurred. Eleven of these patients...

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Source: Hepatitis Weekly (2006-09-11)

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