Hepatitis B Virus

Chronic hepatitis B liver cirrhosis involves angiotensinogen polymorphisms

Published in Hepatitis Weekly, September 25th, 2006

According to recently published research from the People's Republic of China, chronic hepatitis B liver cirrhosis involves angiotensinogen promoter polymorphisms chronic hepatitis B liver cirrhosis is associated with angiotensinogen (AGT) promoter polymorphisms.

"It is known that the renin-angiotensin system (RAS) regulates fibrosis. Polymorphisms in the genes of the RAS may contribute to the outcome of liver cirrhosis.

"AGT, mainly produced in the liver, is the substrate of renin. The aim of this study was to determine whether polymorphisms in the promoter region of the AGT gene are associated with liver cirrhosis in patients with chronic hepatitis...

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Source: Hepatitis Weekly (2006-09-25)

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