Hepatitis C Virus

New findings in hepatitis C virus described from Italy and the United States

Published in Hepatitis Weekly, October 9th, 2006

Data on hepatitis C virus are outlined in reports from Italy and the United States.

Study 1: Recent research from Italy has chronicled low serum tryptophan (TRP) levels, reduced macrophage IDO activity, and high frequency of psychopathology in hepatitis C virus (HCV) patients.

"Indoleamine 2,3-dioxygenase (IDO), a key enzyme of TRP metabolism, is induced in various tissues of patients with bacterial and viral infection or with neoplastic diseases. This induction is considered the main cause of the decreased serum TRP levels, the reduced brain serotonin synthesis and the occurrence of psychopathological disorders often detected in patients with...

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Source: Hepatitis Weekly (2006-10-09)

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