Hepatitis C Virus
Hepatitis C virus neutralization effect reduced by high-density lipoproteins
Published in Hepatitis Weekly, October 23rd, 2006
"The neutralizing activity of anti-HCV antibodies is attenuated by a factor present in human sera, which has been proposed to be HDLs. HDLs have also been shown to facilitate the entry of HCV pseudoparticles (HCVpp) into target cells.
"Here, the aim of the study was to determine whether HDL-mediated facilitation of HCVpp and infectious HCV (HCVcc) entry and attenuation of neutralization are two related phenomena," wrote C. Voisset and colleagues, Institut...
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Source: Hepatitis Weekly (2006-10-23)
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