Published in Hepatitis Weekly, October 30th, 2006
"HBV covalently dosed circular DNA (cccDNA) is responsible for viral persistence in the natural course of chronic HBV infection and during prolonged antiviral therapy and serves as the template for the production of HBV pregenomic RNA (pgRNA), the primary step in HBV replication," wrote A. Laras and colleagues, Henry Dunant Hospital.
"In this study, we have developed and applied sensitive and specific quantitative real-time...
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