Published in Hepatitis Weekly, October 30th, 2006
"A large share of hepatitis C virus amino acid sequence variation is concentrated within two HVRs located at the N-terminus of the E2 envelope glycoprotein (HVR1 and HVR2)," wrote M. Troesch and colleagues, CHU Mere-Enfant Sainte-Justine.
"Interhost and intrahost comparison of 391 E2 sequences derived from 17 subjects infected with HCV using amino acid entropy revealed clustering of amino acid variability at a third site (residues 431-466), which was termed HVR3.
"Genetic distance analysis...
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