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Hepatitis C Virus

Chronic hepatitis C fibrosis severity is associated with ABO blood group

Published in Hepatitis Weekly, November 6th, 2006

Recent research from France has chronicled the association between ABO blood group and fibrosis severity in chronic hepatitis C virus (HCV) infection.

"The progression of fibrosis in HCV infection is a process in which genes interact with environmental factors. A 'clotting process' is involved in fibrogenesis.

"ABO blood group distribution is associated with thrombotic disease, non-O blood group increasing the risk of venous thrombosis. The aim of the study was to investigate whether ABO blood type contributes to the severity of fibrosis," wrote A. Poujol-Robert and colleagues, University of Paris.

"We studied blood group...

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