Hepatitis B Virus
Research from South Korea and Canada has provided new hepatitis B virus data
Published in Hepatitis Weekly, December 11th, 2006
Study 1: A study from South Korea has reported on resistance to adefovir dipivoxil (ADV) in lamivudine (LMV) resistant chronic hepatitis B virus (HBV) patients treated with ADV.
"ADV is a potent nucleotide analogue against both the wild-type and LMV resistant HBV. The cumulative incidence of ADV resistant mutations in the nucleoside/-tide treatment naive chronic hepatitis B patient (CHB) at weeks 48, 96, and 144 was 0, 0.8-3%, and approximately 5.9%, respectively.
"The aim of this study was to characterise the genotypic and phenotypic mutation profiles to ADV...
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Source: Hepatitis Weekly (2006-12-11)
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