Tuberculosis Risk Factors

Studies from Leiden University, Department of Infectious Diseases have provided new information about tuberculosis risk factors

Published in Hepatitis Weekly, December 18th, 2006

A new study, "Risk factors of acute hepatic failure during antituberculosis treatment: two cases and literature review," is now available. According to a study from Leiden, Netherlands, "Hepatotoxicity is a well-known side effect of antituberculosis treatment (ATT). If not recognised in time, drug-induced hepatitis can develop, which may rapidly progress to acute liver failure."

"We describe two patients with acute hepatic failure caused by ATT, whose pretreatment liver function had been normal. Both patients successfully underwent liver transplantation. Possible risk factors predisposing towards ATT-induced hepatic failure were evaluated, and at least four risk factors...

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Source: Hepatitis Weekly (2006-12-18)

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