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Hepatitis C Virus Therapy

New findings from Erasmus University, Department of Surgery in the area of hepatitis c virus therapy published

Published in Hepatitis Weekly, December 25th, 2006

Scientists discuss in "Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha" new findings in hepatitis C virus. "Chronic hepatitis C virus (HCV) infection is the leading indication for liver transplantation. Clinical evidence suggests that particular immunosuppressive agents can have an influence on HCV recurrence," researchers in Rotterdam, Netherlands report.

"Cyclosporine A (CsA) specifically inhibits HCV replication through blocking the viral RNA polymerase enzyme NS5B. In this study, we investigated the effect of mycophenolic acid (MPA) and other immunosuppressants on HCV replication. MPA and other...

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