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Hepatitis B Virus Cell Biology

New hepatitis b virus cell biology research reported from Ajou University, Department of Microbiology

Published in Hepatitis Weekly, January 1st, 2007

Current study results from the report, "Intracellular antibody fragment against hepatitis B virus X protein does not inhibit viral replication," have been published. According to a study from Suwon, Korea, "Replication of the hepatitis B virus is suppressed by deficiency of the X protein. Although several molecules that block cellular targets of X protein reduce the production of hepatitis B virus progeny, the effect of a specific inhibitor of X protein on viral replication has not been investigated."

"To block X protein specifically, we adopted an intracellular expression approach using H7 single chain variable fragment (H7scFv), an antibody fragment against X protein....

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