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Licensing Agreements

Schering-Plough licenses rights to oral hepatitis B treatment with Valeant and Metabasis

Published in Hepatitis Weekly, January 8th, 2007

Schering-Plough Corporation (SGP) announced the signing of definitive licensing agreements with Valeant Pharmaceuticals International (VRX) and Metabasis Therapeutics, Inc. (MBRX) for exclusive worldwide development and commercial rights to pradefovir, an investigational oral antiviral compound currently in phase 2 clinical development for the treatment of chronic hepatitis B.

Valeant licensed pradefovir from Metabasis in 2000 and has been conducting clinical trials to evaluate the safety and efficacy of pradefovir for compensated chronic hepatitis B. Pradefovir is a pro-drug of PMEA that uses Metabasis' HepDirect technology to enable higher concentrations of the drug...

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