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Hepatitis B Virus Therapy

Researchers at Mount Sinai School of Medicine, Department of Medicine publish new data on hepatitis b virus therapy

Published in Hepatitis Weekly, January 15th, 2007

New research, "Effect of switching to tenofovir with emtricitabine in patients with chronic hepatitis B failing to respond to an adefovir-containing regimen," is the subject of a report. According to recent research from the United States, "In patients with chronic hepatitis B, long-term use of lamivudine is limited by resistance mutations. Adefovir dipivoxil has a very low rate of resistance, but there have been recent reports describing resistance mutations."

"Tenofovir disoproxil fumarate and emtricitabine show potent activity against wild-type and lamivudine-resistant hepatitis B virus. We describe a series of seven HIV-seronegative patients who failed to achieve...

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