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Hepatitis C Therapy

InterMune initiates phase Ia trial for ITMN-191 in collaboration with Roche

Published in Hepatitis Weekly, January 15th, 2007

InterMune, Inc., (ITMN) announced that the company and its partner Roche have received approval of the European Clinical Trial Authorization for ITMN-191, the NS3/4A protease inhibitor, and have initiated a phase Ia clinical trial evaluating ITMN-191 for the treatment of chronic hepatitis C virus (HCV) infection.

The phase Ia trial will assess safety, tolerability, pharmacokinetics, and food affect in a double-blind, placebo-controlled, single-ascending-dose study. The study is being conducted at 1 clinical trial site in Europe and will enroll approximately 74 healthy volunteers. InterMune expects to dose the first patient with ITMN-191 sometime in early January...

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