Alcoholism
Scientists at Institute of Hepatology, Division of Medicine target alcoholism
Published in Hepatitis Weekly, January 22nd, 2007
A report, "Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis," is newly published data in Hepatology. According to recent research from the United Kingdom, "Previous studies suggest reduced hepatic endothelial nitric oxide synthase activity contributes to increased intrahepatic resistance. Asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, undergoes hepatic metabolism via dimethylarginine-dimethylamino-hydrolase, and is derived by the action of protein-arginine-methyltransferases."
"Our study assessed whether ADMA, and its stereo-isomer symmetric dimethylarginine (SDMA), are...
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Source: Hepatitis Weekly (2007-01-22)
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