Hepatitis Immunology
Research results from University of Roma Tor Vergata update knowledge of hepatitis immunology
Published in Hepatitis Weekly, February 5th, 2007
New research, "A novel mutation of varicella-zoster virus associated to fatal hepatitis," is the subject of a report. According to recent research published in the Journal of Clinical Virology, "Lethal varicella in immunocompetent hosts is rare and its pathogenesis is largely unknown. The discovery of glycoprotein E (gE) mutants showing attributes consistent with increased virulence in vitro and in animal models, provided a possible molecular mechanism underlying a more aggressive virus infection."
"However, these mutants have never been associated with unusually severe clinical cases. To varicella-zoster virus (VZV) mutations that correlate with increased...
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Source: Hepatitis Weekly (2007-02-05)
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