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Hepatitis B Virus Genetics

Research from University of Hong Kong in hepatitis B virus genetics provides new insights

Published in Hepatitis Weekly, February 26th, 2007

New research, "Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection," is the subject of a report. According to a study from Hong Kong, "Exposure to HBV leads to a distinct clinical course which is partially pertained to host genetic variability. We aimed to study polymorphisms of type I interferon receptor 1 (IFNAR1) promoter and their potential effects on chronic HBV infection."

"Polymorphisms of IFNAR1 promoter were identified in 320 chronic hepatitis B patients, 148 spontaneously recovered individuals, 148 healthy Chinese donors and 114 Caucasians. Their functional capability in driving reporter gene...

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