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Hepatitis C Virus

Research on hepatitis C virus published by scientists at Osaka University, Research Institute for Microbial Disease

Published in Hepatitis Weekly, February 26th, 2007

Scientists discuss in "Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis" new findings in hepatitis C virus. According to recent research from Osaka, Japan, "Hepatitis C virus (HCV) is a major cause of chronic liver disease that frequently leads to steatosis, cirrhosis, and eventually hepatocellular carcinoma (HCC). HCV core protein is not only a component of viral particles but also a multifunctional protein because liver steatosis and HCC are developed in HCV core gene-transgenic (CoreTg) mice."

"Proteasome activator PA28gamma/REGgamma regulates host and viral proteins such as nuclear hormone receptors and HCV core...

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