Allergies Immunology
Researchers from National Heart Lung and Blood Institute provide details of new studies and findings in the area of allergies immunology
Published in Hepatitis Weekly, March 5th, 2007
A new study, "Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of tolerance," is now available. "Current evidence suggests that drug-induced liver disease can be caused by an allergic response (drug-induced allergic hepatitis, DIAH) induced by hepatic drug-protein adducts. The relatively low incidence of these reactions has led us to hypothesize that tolerogenic mechanisms prevent DIAH from occurring in most people," scientists in the United States report.
"Here, we present evidence for the existence of one of these regulatory pathways. Following a hepatotoxic dose of acetaminophen in C57Bl/6 mice,...
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Source: Hepatitis Weekly (2007-03-05)
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