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Hepatitis C Virus Prevention

Research from Abbott Laboratories broadens understanding of hepatitis C virus prevention

Published in Hepatitis Weekly, March 12th, 2007

Scientists discuss in "Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro" new findings in hepatitis C virus. "The combinations of Abbott Hepatitis C virus (HCV) polymerase A-782759 with either Boehringer Ingelheim HCV NS3 protease inhibitor BILN-2061 or interferon (IFN) displayed additive to synergistic relationships over a range of concentrations of two-drug combination. Treatment of HCV replicon with A-782759, IFN or BILN-2061 for about 16 days resulted in dramatic reductions in HCV RNA (5.1, 3.0 and 3.9 log10 RNA copies, respectively)," scientists writing in the journal Antiviral Research report.

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