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Hepatitis B Virus

New hepatitis B virus findings from Institute Pasteur published

Published in Hepatitis Weekly, March 19th, 2007

A new study, "The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription," is now available. "The hepatitis B virus infects more than 350 million people worldwide and is a leading cause of liver cancer. The virus encodes a multifunctional regulator, the hepatitis B virus X protein (HBx), that is essential for virus replication," researchers in Paris, France report.

"HBx is involved in modulating signal transduction pathways and transcription mediated by various factors, notably CREB that requires the recruitment of the co-activators CREB-binding protein (CBP)/p300. Here we investigated the role...

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