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Hepatitis C Virus Cell Biology

Research from University of Genoa, Department of Internal Medicine in hepatitis C virus cell biology provides new insights

Published in Hepatitis Weekly, April 30th, 2007

New research, "Soluble apoptosis molecules in primary biliary cirrhosis: analysis and commitment of the Fas and tumour necrosis factor-related apoptosis-inducing ligand systems in comparison with chronic hepatitis C," is the subject of a report. According to a study from Genoa, Italy, "Apoptosis in the liver is generated mainly by the Fas system. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has been proposed recently as a new apoptotic inducer."

"In the liver environment hepatocytes and biliary epithelial cells express TRAIL receptors which are up-regulated by increased levels of bile acids and during viral hepatitis. As for FasL, a soluble form of...

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