Hepatitis C Virus Genetics
Scientists at University Autonoma of Barcelona target hepatitis C virus genetics
Published in Hepatitis Weekly, April 30th, 2007
A report, "Genetic and catalytic efficiency structure of an HCV protease quasispecies," is newly published data in Hepatology. "The HCV nonstructural protein (NS)3/4A serine protease is not only involved in viral polyprotein processing but also efficiently blocks the retinoic-acid-inducible gen I and Toll-like receptor 3 signaling pathways and contributes to virus persistence by enabling HCV to escape the interferon antiviral response. Therefore, the NS3/4A protease has emerged as an ideal target for the control of the disease and the development of new anti-HCV agents," scientists in Spain report.
"Here, we analyzed, at a high resolution (approximately 100...
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Source: Hepatitis Weekly (2007-04-30)
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