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Hepatitis B Virus

Research from Institute of Biochemistry and Cell Biology in hepatitis B virus provides new insights

Published in Hepatitis Weekly, May 7th, 2007

New research, "Identification and characterization of peptides that interact with hepatitis B virus via the putative receptor binding site," is the subject of a report. According to a study from Shanghai, People's Republic of China, "A direct involvement of the PreS domain of the hepatitis B virus (HBV) large envelope protein, and in particular amino acid residues 21 to 47, in virus attachment to hepatocytes has been suggested by many previous studies. Several PreS-interacting proteins have been identified."

"However, they share few common sequence motifs, and a bona fide cellular receptor for HBV remains elusive. In this study, we aimed to identify PreS-interacting...

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