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Hepatitis B Virus Prevention

Research in the area of hepatitis B virus prevention reported from Erasmus University

Published in Hepatitis Weekly, June 4th, 2007

Investigators publish new data in the report "Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B. Regulatory T cells (Treg) play a key role in the impaired immune response that is typical for a chronic Hepatitis B virus (HBV) infection. To gain more insight in the mechanism that is responsible for this impaired immune response, the effect of viral load reduction resulting from treatment with the nucleotide analogue adefovir dipivoxil on the percentages of Treg and HBV-specific T-cell responses was analyzed," scientists in Netherlands report.

"Peripheral blood mononuclear cells (PBMC) of 12...

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